Scanning and combinatorial library services – Save 20% with code TRY-BXPLIB-20

Genome editing

High-throughput design for CRISPR experiments

Genetic modification

CRISPR-powered genome editing has enabled significant improvements in the ability to fine-tune genomes. Originally discovered as an mRNA-based adaptive immune response in E. coli, the CRISPR/Cas9 system contains both guide RNA for sequence-specific targeting and a Cas9 endonuclease that removes foreign DNA and allows integration of synthetic DNA into the host genome. That synthetic DNA is designed to specifically target a region in the host genome and make alterations (e.g. add genes, remove genes, correct mutations).

Genetic modification

Enhance productivity in genome editing workflows

The BioXp™ system enhances productivity during the design phase of the customer’s product development cycle by enabling rapid, automated synthesis of gene fragments, clones, and variant libraries. With the BioXp™ system, scientists can perform rapid, high-throughput gene synthesis and cloning of mRNA expression cassettes, regardless of vector size and complexity. In addition, our Gibson Assembly® RapidAMP™ technology — which permits cell-free amplification of microgram quantities of DNA — means plasmid design no longer has to be tethered to an E. coli cloning system. Our Gibson Assembly® RapidAMP™ technology combines cloning and vector amplification in smaller mini-circle plasmids absent E. coli-based genes, thus improving overall transfection efficiency.

Learn more

Contact us

The expertise of our scientists, engineers and supporting teams are at your service! Submit the form below and/or call us at 858.526.3080.

Your personal data is handled according to our privacy policy. In accordance with California data privacy laws, California residents may obtain information about the categories of personal information we are collecting and the purposes for which personal information is collected and used here: California Privacy Policy. In addition, if you are located within a distributor territory, you may be contacted directly by them.